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Titlebook: Anhedonia: Preclinical, Translational, and Clinical Integration; Diego A. Pizzagalli Book 2022 The Editor(s) (if applicable) and The Autho

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期刊全称Anhedonia: Preclinical, Translational, and Clinical Integration
影响因子2023Diego A. Pizzagalli
视频video
发行地址Equips readers to develop a better understanding of the neurobiology, assessment, and treatment of anhedonia.Reviews exhaustively the burgeoning preclinical and clinical literature on anhedonia and mo
学科分类Current Topics in Behavioral Neurosciences
图书封面Titlebook: Anhedonia: Preclinical, Translational, and Clinical Integration;  Diego A. Pizzagalli Book 2022 The Editor(s) (if applicable) and The Autho
影响因子.Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson‘s Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation,synthesis and integration of theories and empirical findings focused on anhedonia..Organized across five parts, the handbook starts with chapters on the history, etiology, and assessments of anhedonia (
Pindex Book 2022
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Anhedonia in Depression and Bipolar Disorderent theoretical models posit a key role for reward hyposensitivity in BD depression, unlike studies in MDD, studies in BD do not clearly show evidence for reduced reward-related activation in striatal or other brain regions. Although further research is needed, the evidence to date hints at a diverg
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Anhedonia in Schizophrenia cognitive control. We will review studies that utilized various types of rewards (e.g., monetary, social), in order to draw conclusions regarding whether findings vary by reward type. We will then discuss how modern assessment methods may best incorporate each of the mechanisms, to provide a more f
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Anhedonia, Hyperkatifeia, and Negative Reinforcement in Substance Use Disordershemical neurocircuitry changes that are associated with conditioned hyperkatifeia/anhedonia. The overall hypothesis is that the shift in motivation toward negative reinforcement in addiction reflects the allostatic misregulation of hedonic tone, such that drug taking makes anhedonia worse during the
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Anhedonia in Anxiety Disordersdonia is not explicitly considered within prevailing theoretical models or treatment approaches of anxiety. Our goal, therefore, is to review what is known about anhedonia within the anxiety disorders and then integrate this knowledge into a functional perspective to consider how anhedonia could mai
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