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Titlebook: Angiotensin Receptors; Juan M. Saavedra,Pieter B. M. W. M. Timmermans Book 1994 Springer Science+Business Media New York 1994 Angiotensin

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期刊全称Angiotensin Receptors
影响因子2023Juan M. Saavedra,Pieter B. M. W. M. Timmermans
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图书封面Titlebook: Angiotensin Receptors;  Juan M. Saavedra,Pieter B. M. W. M. Timmermans Book 1994 Springer Science+Business Media New York 1994 Angiotensin
影响因子From molecular biology to clinical applications of selectivereceptor blockade, the present volume compiles the latest advances ofthisemerging field. Of particular importance is the attention giventothe newly discovered AT.2. receptors, and the physiology andpathophysiology of angiotensin receptor subtypes. The book willprovide clinicians treating cardiovascular disease and hypertensionwith a clearer understanding of this therapeutically important andcomplicated hormone.
Pindex Book 1994
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The European Union in International Affairsrd the design and synthesis of AT.-specific ligands. However, as losartan (DuP 753). and numerous other AT.-selective antagonists. progress through the clinical departments. of pharmaceutical companies, one is left to consider the clinical consequence of AT. receptor activation. Although at present
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EU Policies towards Latin America,ignaling properties. The pharmacology of AT. receptors is the focus of this chapter; AT. receptors. as well as cytosolic and nuclear angiotensin-binding proteins. have been described elsewhere in this book and are not covered here.
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Interdisciplinary Studies in Human Rightssin system during conditions of infarction-induced cardiac decompensation engenders increases in circulating levels of angiotensin II (ANG II), a major pressor agent.. To reduce the work load on this already compromised ventricle and possibly prevent the associated detrimental changes in chamber geo
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Interdisciplinary Studies in Human Rightsgiotensin receptor. This differentiation is particularly germane in congestive heart failure because this is a clinical syndrome in which the renin—angiotensin system is activated. and converting enzyme inhibition is now conventional therapy for this disease.
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Defining Angiotensin Receptor Subtypes,ibited one population of ANG II binding sites, whereas PD 123177 selectively inhibited the other losartan-resistant site.. A similar observation was independently established by using losartan and a novel peptide ligand, CGP 42112A, which also showed selectivity for the losartan-resistant site.. Sub
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Medicinal Chemistry of Angiotensin II Antagonists,e ANG II receptor antagonists would lack the disadvantages associated with peptide ANG II receptor antagonists and would also be potentially more selective than ACE inhibitors for blocking the RAS was an attractive but elusive strategy until 1982 when Furukawa and co-workers at Takeda Chemical Indus
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Pharmacology of AT2 Receptors,ignaling properties. The pharmacology of AT. receptors is the focus of this chapter; AT. receptors. as well as cytosolic and nuclear angiotensin-binding proteins. have been described elsewhere in this book and are not covered here.
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