Titlebook: Androgen Excess Disorders in Women; Ricardo Azziz,John E. Nestler,Didier Dewailly Book 2007 Humana Press 2007 Diabetes.infertility.insulin

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Androgens Throughout the Life of Womenoducts of the adrenal zona reticularis, whereas A4 and testosterone are synthesized in both the ovary and adrenal; substantial quantities of testosterone arise from peripheral conversion from A4. Modest changes in circulating levels of testosterone occur during the ovarian cycle of women during the

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Ovarian and Adrenal Androgen Biosynthesis and Metabolismhat convert steroid precursors to the final active products. Both the adrenal and ovary produce dehydroepiandrosterone (DHEA), the principal precursor of androgens and estrogens. The key enzyme in DHEA production is P450c17, which catalyzes both 17α-hydroxylation and 17,20-lyase activities. The 17,2

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Physiological Effects of Androgens in Womenssues of excess. Only recently have we become aware that androgens play an important role in many aspects of the health and well-being of women. From sexual orientation to brain development to bone health, androgens are closely intertwined with estrogens, and only by understanding the former can we

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