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Titlebook: Analytical Use of Fluorescent Probes in Oncology; Elli Kohen,Joseph G. Hirschberg Book 1996 Springer Science+Business Media New York 1996

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Fluorescence-Lifetime Based Sensing in Tissues and Other Random Media with Measurements of Photon Mon-invasive biochemical sensing in tissues. Fluorescence intensity and fluorescence lifetime spectroscopies are established methods by which fluorophores can provide sensing in dilute, non-scattering samples. However, fluorescence intensity or fluorescence lifetime spectroscopy in tissues or other s
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Spectroscopy and Tomography of Tissues in the Frequency-Domain, the optical parameters of a turbid medium can be obtained from time resolved measurements of short light pulses propagating in the medium (Patterson et al, 1991a). Essentially, a fit of the intensity as a function of time, measured at some distance from the source, can provide separately the values
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Fret Microscopy in Cellular Signal Transduction,roteins on and in intact cells is lacking. Myriad factors determine the pleiotropic responses of a cell after stimulation. They are mediated to a large extent by interactions of the signaling proteins: binding to cofactors, subcellular (re)localization, covalent processing, and specific binary and h
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Recent Developments in Fluorescence Spectroscopy,domain method and the availability of suitable laser sources and detectors now provides remarkable resolution of complex intensity and anisotropy decays. At present the applications of fluorescence are more limited by the lack of suitable fluorophores than by instrumentation. In particular, the info
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Sub-Cellular Localization of Second Generation PDT Photosensitizers Studied by MicrospectrofluoromeHowever, the low specificity of P2 delivery to tumor tissues and the lack of light absorption of the mixture of porphyrins constituting P2 in the 650 – 800 nm range, where tissues maximally transmit precludes the use of PDT for large tumor masses. In the case of skin tumors, selectivity has been rec
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