| 期刊全称 | Amorphous Solid Dispersions | | 期刊简称 | Theory and Practice | | 影响因子2023 | Navnit Shah,Harpreet Sandhu,A. Waseem Malick | | 视频video | | | 发行地址 | Provides comprehensive coverage of theoretical and practical aspects of amorphous formulation development.Emphasizes state-of-the-art, cutting-edge technologies in the field.Presents case studies of m | | 学科分类 | Advances in Delivery Science and Technology | | 图书封面 |  | | 影响因子 | .This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characterization of amorphous solid dispersions, the prediction of long-term stability, and the development of suitable dissolution methods and regulatory aspects. The book also highlights future technologies on the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems..Amorphous Solid Dispersions: Theory and Practice .is a valuable reference to pharmaceutical scientists inter | | Pindex | Book 2014 |
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发表于 2025-3-21 16:40:04
