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Titlebook: Amorphous Drugs; Benefits and Challen Marzena Rams-Baron,Renata Jachowicz,Marian Paluch Book 2018 Springer International Publishing AG 2018

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期刊全称Amorphous Drugs
期刊简称Benefits and Challen
影响因子2023Marzena Rams-Baron,Renata Jachowicz,Marian Paluch
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发行地址Offers a comprehensive review on fundamental concepts and recent advances in the field of amorphous pharmaceuticals.World-leading specialists from different fields present their perspectives on amorph
图书封面Titlebook: Amorphous Drugs; Benefits and Challen Marzena Rams-Baron,Renata Jachowicz,Marian Paluch Book 2018 Springer International Publishing AG 2018
影响因子.This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. ..Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical prod
Pindex Book 2018
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https://doi.org/10.1007/978-3-642-86294-6l” periodic, perfect crystal looks like the one shown in Fig. 2.1 [2]. This pattern corresponds to the inner structure of the material, which can be represented as an array of periodically repeating fragments. The whole structure can be described by defining the repeating fragment (basis) and a set
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https://doi.org/10.1007/978-3-642-86294-6elt co-extrusion are widely adopted techniques in pharmaceutical technology. Conveying of solids, melting, mixing, devolatilization, pumping and pressurization are main stages of HME. In principle, extrusion equipment usually consists of motor as a drive unit, an extrusion barrels enclosing rotating
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Die Einengung der Anwendungsmöglichkeitenn recognized [1], and the trend continues to deteriorate [2]. The poor solubility of these drug candidates imposes great challenges to pharmaceutical scientists and engineers who are ultimately responsible for developing a bioavailable drug product to support the clinical programs and commercializat
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