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Titlebook: Alzheimer’s Disease; A Physician’s Guide Ralph W. Richter (Clinical Professor of Neurology Book 2004 Springer Science+Business Media New

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楼主: Madison
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https://doi.org/10.1007/978-3-662-06635-5ng and, ultimately, treating neurological disorders. Historically, this localizing process has relied on visualizing structural changes in the brain, either under the microscope or more recently with imaging techniques. The last decade of careful investigation has established that aging has no clear
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Ralph W. Richter (Clinical Professor of Neurology Includes supplementary material:
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https://doi.org/10.1007/978-3-658-12801-2e pathology in AD. The theme of this chapter is that genetic analysis—together with pathology investigation—has shown that these diseases share common mechanisms of neurodegeneration, and that they can be grouped into one broadly sketched pathway of pathogenesis.
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https://doi.org/10.1007/978-3-658-07992-5ally and animal model-based experimental observations suggest that anti-inflammatory or immunological strategies may be effective in ameliorating this devastating disease .. Clinical trials testing these therapies are under development.
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https://doi.org/10.1007/978-3-662-06635-5ntact hippocampal neurons .. Even early neurodegenerative processes, such as AD, appear to cause electrophysiological changes before histological lesions, as demonstrated in transgenic mouse models .. Thus, aging is by and large invisible to the microscope, and isolating the neurons most affected by
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1559-0585 early diagnosis of the dementia process is now considered of increasing importance, we focus particularly in several chapters on early changes and preclinical conditions, such as mild cognitive impairment and predementia AD.978-1-4757-4485-9978-1-59259-661-4Series ISSN 1559-0585 Series E-ISSN 2524-4043
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