| 期刊全称 | Alzheimer‘s Disease | | 影响因子2023 | Lit-Fui Lau,Michael A. Brodney | | 视频video | | | 发行地址 | In each volume an overview chapter introduces the newcomer to the topic covered.Series covers hot topics of frontier research summarized by reputed scientists in the field.Review series is topic relat | | 学科分类 | Topics in Medicinal Chemistry | | 图书封面 |  | | 影响因子 | .Alzheimer’s disease (AD) is a neurodegenerative disease that robs the minds of our elderly population. Approximately one in every eight adults over the age of 65 and nearly half of those over 85 are afflicted with this disease. The aging population in developed societies will impose an ever increasing socioeconomic threat in the future. Current medicines for AD patients are mainly symptomatic treatments and a huge unmet medical need exists to slow the progression of this disease. A great deal of research has been dedicated to understanding the pathogenesis of AD from which comes many ideas for intervening with its progression. Some of these ideas have been fast-tracked to clinical trials due to the availability of medicines with proven clinical efficacies for other diseases (e.g. atorvastatin, simvastatin, rosiglitazone and clioquinol) while others represent novel chemical entities (e.g. glycogen synthase kinase-3 inhibitors)...This volume will first review existing cholinesterase inhibitors prescribed for AD patients followed by some target mechanisms with ongoing clinical trials. It offers a glimpse of what our future medicine cabinets may look like for AD patients. It also prov | | Pindex | Book 2008 |
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发表于 2025-3-21 17:38:28
