期刊全称 | Alternative Approaches to Human Blood Resources in Clinical Practice | 期刊简称 | Proceedings of the T | 影响因子2023 | C. Th. Smit Sibinga,P. C. Das,J. C. Fratantoni | 视频video | | 学科分类 | Developments in Hematology and Immunology | 图书封面 |  | 影响因子 | Currently blood is a volatile issue. The safety of blood andthe quantification of transfusion risks have been dominant themes thathave stimulated the development of alternative approaches in thisrapidly developing area. In clinical medicine conventional blood andits components are used in supportive therapies dependent on thechoice of apparent uncritical trigger factors. A compounding factor isdepth of prospective clinical trials for evidence. Such trials incritical care areas would be of enormous value, not only in recordingadverse effects and under-transfusion, but also indicating the valueof decision analysis and cost-effectiveness in transfusion practice.Alternative approaches include the use of cytokines, growth factors,humanised monoclonal antibodies, recombinant plasma factors, and buffycoat derived natural human interferons. These are being increasinglyimplemented in the clinic. Solutions for oxygen transport are beingdeveloped and fibrinogen coated microcapsules are being investigatedfor thrombocytopenia. In surgical patients, various crystalloid andcolloid combinations are explored as volume replacements. To avoidallogeneic transfusions, beneficial blood saving methods in | Pindex | Conference proceedings 1998 |
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