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Titlebook: Algorithms in Bioinformatics; 12th International W Ben Raphael,Jijun Tang Conference proceedings 2012 Springer-Verlag Berlin Heidelberg 201

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RNA Tree Comparisons via Unrooted Unordered Alignments,he . problem, and present a new algorithm which applies to several modes, including global or local, ordered or unordered, and rooted or unrooted tree alignments. Our algorithm generalizes previous algorithms that either solved the problem in an asymmetric manner, or were restricted to the rooted an
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CLIIQ: Accurate Comparative Detection and Quantification of Expressed Isoforms in a Population,Unfortunately, from a computational perspective, identification and quantification of a gene’s isoforms from RNA-Seq data remains to be a non-trivial problem. We propose CLIIQ, a novel computational method for identification and quantification of expressed isoforms from . in a .. Motivated by ideas
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Improved Lower Bounds on the Compatibility of Quartets, Triplets, and Multi-state Characters,n .(.) such that, for any set . of .-state characters, . is compatible if and only if every subset of .(.) characters of . is compatible. We show that for every . ≥ 2, there exists an incompatible set . of ..-state characters such that every proper subset of . is compatible. Thus, . for every . ≥ 2.
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Succinct de Bruijn Graphs,ented in 4. + .(.) bits. This is much smaller than existing ones. The numbers of outgoing and incoming edges of a node are computed in constant time, and the outgoing and incoming edge with given label are found in constant time and . time, respectively. The data structure is constructed in . time u
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