Titlebook: Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction; David Raeburn (Department Head),Mark A. Giembycz ( Book 19

断断续续

Sodium/Potassium/Chloride Co-Transport,larly interesting as frusemide has the same protective profile as two other established anti-asthma drugs, sodium cromoglycate and nedocromil sodium, suggesting that they may share a common mechanism of action.

索赔

Endothelins,s considerable attention in the field of endothelial cell biology was directed towards the isolation and characterization of endotheliumderived modulators of the responsiveness of the underlying vascular smooth muscle. The focus of these studies was on relaxant substances released from the endotheli

receptors

Bradykinin,thesis and release of . and related kinins such as kallidin (Lys-BK, KD) have been reviewed [1–4], and will not be detailed further at present. . exerts numerous effects, via cell-surface receptors, on virtually every mammalian organ, tissue and cell type [4–7]. In addition, kinins have been implica

pineal-gland

Tachykinins and Calcitonin Gene-Related Peptide,ting lung function and activating reflex bronchoconstriction and cough. In this context, capsaicin, the natural pungent ingredient of red peppers, has been extensively used by respiratory physiologists as a chemical probe to activate reflexes arising from the airways.

嬉耍

先兆

Atrial Natriuretic Peptides,. It is now known that this extract contained a peptide, atrial natriuretic peptide (ANP) or atrial natriuretic factor, which is one of a family of hormones known to have an important role in salt and water homeostasis [2–6]. Natriuretic peptides are produced primarily in the heart but are also rele

有说服力

Platelet-Derived Growth Factor, Transforming Growth Factor, and Connective Tissue Growth Factor,nes, either primary or secondary are thought to play a determining role in acute and chronic pathological disorders. The protein cytokines are a unique group of extracellular signalling molecules with critical roles in these processes. Cytokines (also termed growth factors) are pleiotrophic molecule