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Titlebook: Airways Smooth Muscle: Biochemical Control of Contraction and Relaxation; David Raeburn,Mark A. Giembycz (Lecturer) Book 1994 Springer Bas

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Smooth Muscle Myosin: Molecule Conformation, Filament Assembly and Associated Regulatory Enzymes,genous tissue, no proper biochemical studies have been performed on even the major contractile proteins of the airways smooth muscle. For biochemical investigations avian gizzard muscle has been the most common source of smooth muscle tissue since myosin and other contractile proteins can readily be
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Current Concepts on Mechanisms of Force Generation in Airways Smooth Muscle, force which occurs seconds after the addition of a spasmogen followed by, or maybe partly coincident with, a slower, tonic, well maintained contracture. This chapter reviews how airways smooth muscle (ASM) generates force, the contractile proteins involved and their regulation by second and third m
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The Intracellular Calcium Store in Airways Smooth Muscle,a. is approximately 100 µM, while contraction accompanies a rise to above 300 µM [1–5]. The concentration of Ca. in the cytosol is determined by the relative activity of processes which deliver Ca. to the cytosol and which remove Ca. from it. Calcium may be delivered either by influx of extracellula
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Current Concepts on Mechanisms of Force Maintenance in Airways Smooth Muscle,is an important determinant of airway diameter, the resistance to airflow and untimately ventilation of the alveoli. In asthma, control of airway diameter becomes deranged in part because mediators of bronchoconstriction produce inappropriate contraction of the airways smooth muscle. It is probably
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Diglyceride, Protein Kinase C and Force Maintenance of Airways Smooth Muscle,tion and relaxation of airways smooth muscle. Such studies have clearly indicated that many processes are involved in the control of airways smooth muscle tone. In addition, there would appear to be considerable interplay between these biochemical events demonstrating the complexity of the contracti
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