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Titlebook: Aging of Organisms; Heinz D. Osiewacz Book 2003 Springer Science+Business Media Dordrecht 2003 Drosophila.aging.cell.environment.fungi.gen

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general phenomenom of great significance. The underlying processes are very complex and depending on genetic and environment factors. These factors encode or affect a network of interconnected cellular pathways. In no system this network has been deciphered in greater detail. However, the strategy o
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Kin Sum Leung,Jetty Chung-Yung Leers elapsed between verification that the rate of aging was heritable in flies [1] and discovery of the first single mutant that extended lifespan [2]. In the four years since, 10 or so additional genes have been identified. Research in . has also embraced the genomics revolution, revealing key insights into the process of aging itself.
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Aging in ,,s of complex biological problems following the pioneering work of Sidney Brenner and Sir John Sulston who determined the developmental cellular fate map [1]. It is also noted for the early work of Robert Horvitz and colleagues who used the cell lineage map to begin a genetic dissection of programmed cell death [2].
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Yeast Longevity and Aging,sed on the observation that cell division is associated with the deposition of a “bud scar” on the surface of the mother cell. This fundamental aspect of reproduction was subsequently affirmed and expanded upon [2–4], and its cumulative features were directly demonstrated [5].
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