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Titlebook: Ageing and Dementia; Current and Future C Kurt A. Jellinger,Reinhold Schmidt,Manfred Windisc Conference proceedings 2002 Springer-Verlag Wi

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期刊全称Ageing and Dementia
期刊简称Current and Future C
影响因子2023Kurt A. Jellinger,Reinhold Schmidt,Manfred Windisc
视频video
学科分类Journal of Neural Transmission. Supplementa
图书封面Titlebook: Ageing and Dementia; Current and Future C Kurt A. Jellinger,Reinhold Schmidt,Manfred Windisc Conference proceedings 2002 Springer-Verlag Wi
影响因子Epidemiological studies, modern clinical, neuroimaging, neuropsychological, molecular biological, and genetic studies have considerably enhanced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer‘s disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the aged are increasingly acknowledged, and the recognition of mild cognitive impairment as a frequent initial stage of developing dementia is becoming an increasingly important diagnostic and therapeutic problem.The included papers were presented at the 7th International Symposium in Graz, Sept. 2001 and give a timely overview of the current and future concepts of pathogenesis, diagnosis, and treatment strategies of pathological brain ageing and dementias, early recognition of mild cognitive impairment and future possiblities of prevention of dementing processes.
Pindex Conference proceedings 2002
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Frequency of white matter lesions and silent lacunar infarcts, vary largely among studies. Differences in imaging techniques, ratingscales, cut-off points in lesion severity grading and study populations contribute to the variation, in addition to differences in risk factor profiles acrossstudies..In this paper, we will firstly discuss general methodological i
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CT and MRI rating of white matter changes,iation with cognitive impairment was and still is under debate. To assess WMC in a qualitative and/or semiquantitative fashion rating scales have been developed. For MRI most widely used scales are the scales of Manolio, Fazekas, Schmidt, and Scheltens. Most recently a new scale extending earlier su
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Microangiopathy-related cerebral damage and angiotensinogen gene: from epidemiology to biology,l hypertension and age are the best accepted risk factors for MARCD. Genes involved in blood pressure regulation, like genes encoding the proteins of the renin-angiotensin system (RAS) therefore represents good candidate genes for MARCD. Plasma angiotensinogen level is a major determinant of the RAS
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