Titlebook: Advances in Cancer Biomarkers; From biochemistry to Roberto Scatena Book 2015 The Editor(s) (if applicable) and The Author(s), under exclus

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George Hassan PhD, MCIBSE, MIMechE, MIMarE marketing strategies. This limited and “polluted” knowledge may have dramatic consequences for patient. A critical approach towards old and new cancer biomarkers should foster a deepened and useful understanding of the diagnostic and prognostic index of these fundamental parameters of laboratory me

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https://doi.org/10.1007/978-1-4842-6476-8ven though increased levels of NSE have been reported also in non-small cell lung cancer (NSCLC). The level of NSE correlates with tumour burden, number of metastatic sites and response to treatment..NSE can be also useful at diagnosis of NETs and gastroenteropancreatic (GEP)-NETs..Raised serum leve

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Embedded Web Experiences with Tabs,he prognostic value has also been made, particularly in cancer of the breast. Inclusion of these biomarkers in the risk assessment of cancer patients is now considered in the risk-adapted management in carcinoma of the breast. Factors limiting its broader use are discussed with suggestions how these

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https://doi.org/10.1007/978-3-658-41273-9er tests have been adopted successfully into routine clinical care of oncologic patients..This chapter provides an updated background on biomarkers research in oncology, including biomarkers clinical uses, and discusses the problems of discovery pipeline, biomarkers failures and future perspectives.

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Financial Services and the UK Economy,kers such as the urinary transcripts of PCA3 and TMPRSS-ERG fusion are also discussed. To enable further risk stratification tumor markers are often combined with clinical data (e.g. outcome of DRE) in so-called nomograms. Currently the role of magnetic resonance imaging (MRI) in the detection and staging of prostate cancer is being explored.