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Titlebook: Adult T-cell Leukemia/Lymphoma; Toshiki Watanabe,Takuya Fukushima Book 2017 Springer Japan KK 2017 ATL.Anti-CCR4 antibody.HTLV-1.Human T-l

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发表于 2025-3-21 16:47:19 | 显示全部楼层 |阅读模式
期刊全称Adult T-cell Leukemia/Lymphoma
影响因子2023Toshiki Watanabe,Takuya Fukushima
视频video
发行地址Reviews the latest findings on the epidemiology, molecular and genetic features of ATL.Provides discussions on new treatment methods for ATL and infection prevention for HTLV-1.Prepared by authoritati
图书封面Titlebook: Adult T-cell Leukemia/Lymphoma;  Toshiki Watanabe,Takuya Fukushima Book 2017 Springer Japan KK 2017 ATL.Anti-CCR4 antibody.HTLV-1.Human T-l
影响因子This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.
Pindex Book 2017
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https://doi.org/10.1007/978-1-4302-0291-2roviruses. In addition to essential structural and enzymatic genes (., ., ., and .) shared by all retroviral family members, HTLV-1 encodes a unique pX region, which generates two regulatory (Tax, Rex) and five accessory (HBZ, p30, p12, p13, p8) proteins. Among them, Tax and HBZ affect expression le
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Beginning PHP and MySQL E-CommerceCD7. Typical ATL cases are CD4(+)/CD8(−), but there are CD4(−)/CD8(+), CD4/8 double-positive, and double-negative cases. These CD8 antigens are induced on CD4 T cells. ATL cells express CCR4 and CD25, which are common in regulatory T cells. Furthermore, they express other regulatory T cell markers,
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https://doi.org/10.1007/978-1-4302-0291-2able chronic type), 5-year overall survival has improved from 5% in the 1980s to 15% in the 1990s. Comparatively, the median survival time (MST) of patients with indolent ATL (i.e., favorable chronic or smoldering) was 3–7 years with watchful waiting as the standard treatment. Recently, two types of
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Creating the Product Catalog: Part 1dering and favorable ATL has been found to be 52% and 60%, respectively, by a Japanese retrospective survey. However, no solid information has been acquired from prospective trials in determining an appropriate standard of care, although an International Consensus Meeting has recommended considering
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Strings and Regular Expressions, treatment strategy based on the clinical subtypes, prognostic factors, and response to initial therapy is suggested in an international consensus report (Tsukasaki et al. J Clin Oncol 27:453–459, 2009). Patients with acute, lymphoma, or unfavorable chronic subtypes (aggressive ATL) generally have a
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