期刊全称 | Admixture Dynamics, Natural Selection and Diseases in Admixed Populations | 影响因子2023 | Wenfei Jin | 视频video | | 发行地址 | Nominated as an outstanding Ph.D. Thesis by Chinese Academy of Sciences, China.Illustrating signals of natural selection in African American ?.Advancing the understanding on the recent population admi | 学科分类 | Springer Theses | 图书封面 |  | 影响因子 | .In this thesis, Dr. Jin presents the distribution of ancestral chromosomal segments in the admixed genome, which could provide the information needed to explore population admixture dynamics. The author derives accurate population histories of African Americans and Mexicans using genome-wide single nucleotide polymorphisms (SNPs) data. Mapping the genetic background facilitates the study of natural selection in the admixed population, and the author identifies the signals of selection in African Americans since their African ancestors left for America. He further demonstrates that many of the selection signals were associated with African American-specific high-risk diseases such as prostate cancer and hypertension, suggesting an important role these disease-related genes might have played in adapting to their new environment. Lastly, the author reveals the complexity of natural selection in shaping human susceptibility to disease. The thesis significantly advances our understanding of the recent population admixture, adaptation to local environment and its health implications.. | Pindex | Book 2015 |
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书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations影响因子(影响力) 
书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations影响因子(影响力)学科排名 
书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations网络公开度 
书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations网络公开度学科排名 
书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations被引频次 
书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations被引频次学科排名 
书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations年度引用 
书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations年度引用学科排名 
书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations读者反馈 
书目名称Admixture Dynamics, Natural Selection and Diseases in Admixed Populations读者反馈学科排名 
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