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Titlebook: Adhesion Protein Protocols; Elisabetta Dejana,Monica Corada Book 19991st edition Springer Science+Business Media New York 1999

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发表于 2025-3-21 16:07:59 | 显示全部楼层 |阅读模式
期刊全称Adhesion Protein Protocols
影响因子2023Elisabetta Dejana,Monica Corada
视频video
学科分类Methods in Molecular Biology
图书封面Titlebook: Adhesion Protein Protocols;  Elisabetta Dejana,Monica Corada Book 19991st edition Springer Science+Business Media New York 1999
影响因子Adhesion molecules are of fundamental importance in the regulation of immunity, inflammation, tissue remodeling, and embryonic development. They comprise different families of homologous proteins, such as selectins, integrins, cadherins, and immunoglobins. In addition, beyond these groups, other str- tures with adhesive properties, such as proteoglycans, occludin, and CD44, have been characterized recently. An understanding of the type and characteristics of adhesive molecules expressed by the different cell types and the possibility of manipulating their activity promises considerable clinical potential. Antibodies, small peptidic and nonpeptidic molecules, have recently been used to inhibit thrombosis by blocking platelet aggregation or inflammation through inhibition of leukocyte infiltration and adhesion. Inhibitors of adhesive molecules are used in expe- mental systems for the study of tumor growth and dissemination. Among major goals in the field are the identification of new members of the known adhesive protein families and of independent new adhesive structures. After structural characterization, even more demanding is the study of the biological activity of the new protei
Pindex Book 19991st edition
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发表于 2025-3-21 22:58:04 | 显示全部楼层
1064-3745 They comprise different families of homologous proteins, such as selectins, integrins, cadherins, and immunoglobins. In addition, beyond these groups, other str- tures with adhesive properties, such as proteoglycans, occludin, and CD44, have been characterized recently. An understanding of the type
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Bauchemie für das Bachelor-Studium of members of the integrin, selectin, immunoglobulin, and cadherin families of adhesion receptors, and their specific cellular and tissue distribution have only been made possible through the development and use of specific MAbs to these molecules.
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Allegory and Modernity in the Scapigliatura,h vascular endothelium and subendothelial basement membrane—events that precede TC extravasation and then metastasis formation. Preferential interaction between tumor cells and the microvascular endothelium/extracellular matrix of different areas have been reported to contribute to the homing of metastasis (.).
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Allegory and Modernity in the Scapigliatura,which can be followed by firm adhesion of the cells to the vessel wall. It is believed that in some conditions adherent cells can migrate across the endothelial layer and extravasate within the vascular wall (.–.).
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https://doi.org/10.1007/978-3-030-92018-0re, aspects of cell physiology related to the molecules controlling adhesion to neighboring cells (.–.) and to substrate (.), to components of the cytoskeleton (.–.), as well as to extracellular matrix remodeling (.–.) can be studied during the transition from the resting to the migratory/proliferative phenotype.
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Bauchemie für das Bachelor-Studium by this method (.,.). These studies, however, have suggested that the epitopes of native protein consist of 15–22 residues with a smaller subset of 5–6 residues contributing most of the binding energy. It is important to note that these critical residues may not be arranged in a linear sequence (.).
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Introduction: A System of Contradictionselial cell (.). The sequential and coordinated interaction of these leukocyte-endothelial adhesion molecules, in conjunction with the localized generation of leukocyte-selective chemoattractant cytokines, confers a cellular selectivity to these reactions (.,.).
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