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Titlebook: Acute and Long-Term Side-Effects of Radiotherapy; Biological Basis and Wolfgang Hinkelbein,Gregor Bruggmoser,Michael Wann Conference procee

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Egemen Kaymaz,Filiz Senkal Sezerisoeffective response to radiotherapy in normal tissues and tumors (Joiner 1989). This relationship reflects the gradual decrease in radiation effectiveness with lowered doses due to these doses being further and further back “on the shoulder” of the underlying survival curve for the cells at risk.
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Imen Souiden,Zaki Brahmi,Mohamed Nazih Omrind types of target cells or functional tissue units, and their radiosensitivity determine the location and steepness of the dose-response curve in an individual patient. However, the dose-response curve estimated from a group of patients is always flatter than the individual one due to heterogeneity
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Advancements in Health Sciencesand irradiation/surgery for T3 tumors achieved 5-year survival rates up to 40% (Jacobi et al. 1983) and 40%–50% (van der Werf-Messing 1983). 5-Fluorouracil (5-FU), mitomycin C and cisplatin were shown to be useful as radiosensitizers in invasive bladder carcinoma. Rotman et al. (1987) and Russel et
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https://doi.org/10.1007/978-981-97-6875-2 component. If the threshold of potential complete restitution is crossed, the pneumonitis will develop into pulmonary fibrosis (a scar) as a permanent residual (Gross 1977; Slanina et al. 1977; Westcott and Cole 1986; White 1975).
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Springer Proceedings in Materials TBI provides a high immunosuppressive and anti-tumor effect. However, up to 30% of patients develop interstitial pneumonitis which may partially be induced by radiation injury (Weiner et al. 1986; Beelen et al. 1987; Ettinger and Trulock 1991). In 95% of these patients interstitial pneumonitis is l
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https://doi.org/10.1007/978-981-97-4677-4 therapeutic purposes. The numerous experiments designed to elucidate the pathogenesis of radionecrosis pointed out changes occurring in either the stroma or the parenchyma of the tissues as the primary cause of late effects of ionizing radiation.
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