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Titlebook: Hematologic Malignancies: Acute Leukemias; E. H. Estey,S. H. Faderl,H. M. Kantarjian Book 20081st edition Springer-Verlag Berlin Heidelber

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https://doi.org/10.1007/b138346 marrow. Although it is not clear why blasts have a tendency to circulate in some patients and not in others, ALL can be reliably diagnosed using peripheral blood or bone marrow blasts when blasts are in circulation [79]. However, distinguishing blasts from activated lymphocytes is difficult in some
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Verhalten, Kommunikation und Informationhe result of an accumulation of a mosaic of knowledge and experience, which have led to a more profound understanding of the biology of the disease, and at the same time the development of new drugs and treatment strategies. Advances in the understanding of the biology has highlighted significant di
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https://doi.org/10.1007/b138346lts with acute lymphoblastic leukemia (ALL). In recent years, these clinical trials have been supplemented by systematic morphologic, immunophenotyping, cytogenetic and molecular genetic studies, leading to the identification of different risk groups of patients who may warrant individualized treatm
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Faktorausstattung und Güterhandelblastic Leukemia (GMALL). GMALL protocols are administered in hospitals all over Germany and the number of participating centers in Germany increased from 25 in 1981 to 120 in the most recent trial. Up to now seven consecutive trials for adult de novo ALL have been conducted. The major aim of all tr
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Kultur, Gesellschaft und Wirtschafthe presence of monoclonal surface immunoglobulins (sIg), and by chromosomal translocations, usually t(8;14) (q24;q32) and less commonly its variants t(2;8) (p12;q24) or t(8;22) (q24;q11) [1–4]. These translocations lead to rearrangements of the protooncogene c-myc, located at band 8q24 [5]. Recently
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