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Titlebook: Activity-Based Protein Profiling; Benjamin F. Cravatt,Ku-Lung Hsu,Eranthie Weerapana Book 2019 Springer Nature Switzerland AG 2019 Penicil

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发表于 2025-3-21 17:01:41 | 显示全部楼层 |阅读模式
期刊全称Activity-Based Protein Profiling
影响因子2023Benjamin F. Cravatt,Ku-Lung Hsu,Eranthie Weerapana
视频video
发行地址Provides new insights into activity-based protein profiling (ABPP), which uses chemical probes to profile the functional state of enzymes in native biological systems.Focuses on the application of ABP
学科分类Current Topics in Microbiology and Immunology
图书封面Titlebook: Activity-Based Protein Profiling;  Benjamin F. Cravatt,Ku-Lung Hsu,Eranthie Weerapana Book 2019 Springer Nature Switzerland AG 2019 Penicil
影响因子.This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions. .
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https://doi.org/10.1007/978-3-662-05952-4se exhibit polypharmacology across the PARP family. In this review, we discuss the history, development, and current state of the field, highlighting the limitations and opportunities for PARP inhibitor development.
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Physikalische Grundlagen der Optik,lipids and the lipid–protein interaction profile. In this review, we will summarize the recent developments in the field of chemical probes to study lipid biology, especially in immunology, and indicate potential avenues for future research.
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Entwicklung empirischer Methoden,ic profiling methods for their global analysis. We then summarize recent fatty-acylation profiling studies performed in eukaryotic pathogens and during bacterial infections, highlighting how they contribute to functional characterization of fatty-acylation under these contexts.
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,Weiterführungen bisheriger Ergebnisse, Ub modifications, and subsequently controle and degrade these signals, is enormous. In this chapter, we will discuss the current state-of-the-art of activity-based probes, reporter substrates, and other relevant tools based on Ub as recognition element, to study the enzymes involved in the complex system of ubiquitination.
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,Abgasprüfungen - Übersicht und Kritik,rm for high-throughput inhibitor discovery. This review will showcase the development of ABPPs targeting the PADs. In addition, it provides a brief overview of PAD structure and function along with recent advances in PAD inhibitor development.
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Book 2019 science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and b
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