Titlebook: Water and Biomolecules; Physical Chemistry o Kunihiro Kuwajima,Yuji Goto,Masahide Terazima Book 2009 Springer-Verlag Berlin Heidelberg 2009

和平主义

Mapping Protein Folding Landscapes by NMR Relaxation,ions along the protein folding pathway provide an important impetus for the formation of the final natively folded structure of the protein. NMR spectroscopy provides unique insights into the dynamic protein folding process, and during the past 20 years we have seen the development of a wide range o

职业

Mapping Protein Folding Landscapes by NMR Relaxation,ions along the protein folding pathway provide an important impetus for the formation of the final natively folded structure of the protein. NMR spectroscopy provides unique insights into the dynamic protein folding process, and during the past 20 years we have seen the development of a wide range o

遗弃

清唱剧

,Experimental and Simulation Studies of the Folding/Unfolding of Goat α-Lactalbumin,olding/unfolding of the protein, both experimentally and by simulation of the molecular dynamics. Experimentally, the recombinant protein exhibited remarkable destabilization and unfolding-rate acceleration as compared to those of the authentic protein; these differences were caused by the presence

对手

皮萨

Transition in the Higher-order Structure of DNA in Aqueous Solution, Examples include a large discontinuous folding transition between disordered coil and ordered compact states, the phenomenon of intrachain segregation, in which folded and unfolded parts coexist along the chain, and the multi-stability between different “phases,” which implies the importance of dyn

STANT

Generalized-Ensemble Algorithms for Studying Protein Folding,is difficulty by performing a random walk in potential energy space and other parameter space. From only one simulation run, one can obtain accurate canonical-ensemble averages of physical quantities as functions of temperature and other parameters of the sytem by the single-histogram and/or multipl

Flirtatious

thalamus

Protein Folding and Binding: Effective Potentials, Replica Exchange Simulations, and Network Modelsy landscapes. We have developed an approach that makes use of the combined power of replica exchange simulations and a network model for kinetics. We carry out replica exchange simulations to generate a very large set of states using an all-atom effective potential function and construct a kinetic m

pacific

Protein Folding and Binding: Effective Potentials, Replica Exchange Simulations, and Network Modelsy landscapes. We have developed an approach that makes use of the combined power of replica exchange simulations and a network model for kinetics. We carry out replica exchange simulations to generate a very large set of states using an all-atom effective potential function and construct a kinetic m