Overview: Includes effective strategies for decreasing tobacco use and preventing initiation that uses a translational approach in which genetic, neurobiological, individual, and cultural factors motivating tob.Tobacco kills more people worldwide than any legal or illegal drug; the collective benefits of quitting smoking are plentiful, from improved health, increased life expectancy, and fewer sick days to less stress on families and health care providers. Tobacco use and addiction depend on the complex interplay of neurochemical, genetic, personal, and social factors—and nicotine, as the prin
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