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书目名称Enzyme Kinetics in Drug Metabolism影响因子(影响力)<br> http://impactfactor.cn/if/?ISSN=BK0313090<br><br> <br><br>书目名称Enzyme Kinetics in Drug Metabolism影响因子(影响力)学科排名<br> http://impactfactor.cn/ifr/?ISSN=BK0313090<br><br> <br><br>书目名称Enzyme Kinetics in Drug Metabolism网络公开度<br> http://impactfactor.cn/at/?ISSN=BK0313090<br><br> <br><br>书目名称Enzyme Kinetics in Drug Metabolism网络公开度学科排名<br> http://impactfactor.cn/atr/?ISSN=BK0313090<br><br> <br><br>书目名称Enzyme Kinetics in Drug Metabolism被引频次<br> http://impactfactor.cn/tc/?ISSN=BK0313090<br><br> <br><br>书目名称Enzyme Kinetics in Drug Metabolism被引频次学科排名<br> http://impactfactor.cn/tcr/?ISSN=BK0313090<br><br> <br><br>书目名称Enzyme Kinetics in Drug Metabolism年度引用<br> http://impactfactor.cn/ii/?ISSN=BK0313090<br><br> <br><br>书目名称Enzyme Kinetics in Drug Metabolism年度引用学科排名<br> http://impactfactor.cn/iir/?ISSN=BK0313090<br><br> <br><br>书目名称Enzyme Kinetics in Drug Metabolism读者反馈<br> http://impactfactor.cn/5y/?ISSN=BK0313090<br><br> <br><br>书目名称Enzyme Kinetics in Drug Metabolism读者反馈学科排名<br> http://impactfactor.cn/5yr/?ISSN=BK0313090<br><br> <br><br>
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发表于 2025-3-21 21:19:48
Methods in Molecular Biologyhttp://image.papertrans.cn/e/image/313090.jpg
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发表于 2025-3-22 02:44:20
https://doi.org/10.1007/978-1-0716-1554-6Kinetic models; Drug-drug interactions; Drug metabolizing enzymes; Regulatory guidelines; Drug transport
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发表于 2025-3-22 08:12:24
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发表于 2025-3-22 09:29:01
Africa-EU Partnership on Energy major cause of clinically significant drug–drug interactions. This chapter defines the four reversible mechanisms of inhibition exhibited by drugs: competitive, noncompetitive, uncompetitive, and mixed competitive/noncompetitive. An in vitro procedure to determine the potential of a drug to be a re
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发表于 2025-3-22 16:36:35
A. M. Vasiliev,D. A. Degterev,T. M. Shawt a million compared to the rate of the same reaction in the absence of the enzyme. In contrast to traditional catalytic enzymes, the family of cytochrome P450 (CYPs) enzymes are catalytically promiscuous and thus they possess remarkable versatility in substrates. The great diversity of reactions ca
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发表于 2025-3-22 19:58:06
Célestine L. D. Mangue,Jean Gonondoe. In all but the very simplest in vitro system, these drug concentrations can be influenced by a variety of nonspecific binding reservoirs that can reduce the available concentration to the enzyme system(s) under investigation. As a consequence, the apparent kinetic parameters, such as . or ., that
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发表于 2025-3-23 00:31:25
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发表于 2025-3-23 02:06:45
Imperialism and U.S.-Africa Relationsf their crystallographic protein structures. Fortunately, despite low sequence similarity between different families of drug-metabolizing CYPs, there exists a high degree of structural homology within the superfamily. This similarity in the protein fold allows for a direct comparison of the structur
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发表于 2025-3-23 08:32:34
https://doi.org/10.1007/978-1-349-06218-8hey translocate drugs, as well as endogenous molecules and toxins, across membranes using ATP hydrolysis, or ion/concentration gradients. In general, drug transporters are expressed ubiquitously, but they function in drug disposition by being concentrated in tissues such as the intestine, the kidney