Synchronism 发表于 2025-3-28 17:44:50

Crystal Structures of Drug-Metabolizing CYPsf their crystallographic protein structures. Fortunately, despite low sequence similarity between different families of drug-metabolizing CYPs, there exists a high degree of structural homology within the superfamily. This similarity in the protein fold allows for a direct comparison of the structur

Hyperalgesia 发表于 2025-3-28 22:12:49

The Structure and Mechanism of Drug Transportershey translocate drugs, as well as endogenous molecules and toxins, across membranes using ATP hydrolysis, or ion/concentration gradients. In general, drug transporters are expressed ubiquitously, but they function in drug disposition by being concentrated in tissues such as the intestine, the kidney

tinnitus 发表于 2025-3-28 23:37:47

Enzyme Kinetics of Oxidative Metabolism—Cytochromes P450otics). The versatility of these enzymes results in some unusual kinetic properties, stemming from the simultaneous interaction of multiple substrates with the CYP active site. Often, the CYPs display kinetics that deviate from standard hyperbolic saturation or inhibition kinetics. Non-Michaelis-Men

嬉耍 发表于 2025-3-29 04:19:43

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灌输 发表于 2025-3-29 08:36:53

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阻挡 发表于 2025-3-29 12:16:41

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同来核对 发表于 2025-3-29 18:39:56

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Organization 发表于 2025-3-29 20:06:58

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GLUE 发表于 2025-3-30 03:42:06

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BRUNT 发表于 2025-3-30 08:00:06

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查看完整版本: Titlebook: Enzyme Kinetics in Drug Metabolism; Fundamentals and App Swati Nagar,Upendra A. Argikar,Donald Tweedie Book 2021Latest edition Springer Sci