放逐
发表于 2025-3-27 00:43:17
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aquatic
发表于 2025-3-27 04:43:32
Increasing Agricultural Productivity, during chemotherapy treatment serves as a basis to discuss an example of sensitivity analysis. Second, an example of doxorubicin bioactivation is used for discussing points of consideration when constructing and analyzing network models of drug metabolism.
Encephalitis
发表于 2025-3-27 06:06:30
Fundamentals of Enzyme Kinetics: Michaelis-Menten and Non-Michaelis–Type (Atypical) Enzyme KineticsDrug Metab Rev 36:231–242, 2004). Several cytochromes P450 (CYPs) have large active sites that enable binding of multiple molecules (Yano et al., J Biol Chem 279:38091–38094, 2004; Wester et al., J Biol Chem 279:35630–35637, 2004). Thus, atypical kinetics are not uncommon in in vitro drug metabolism studies.
forecast
发表于 2025-3-27 12:21:34
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边缘
发表于 2025-3-27 15:21:55
Numerical Methods for Modeling Enzyme Kineticsequations in the analysis of metabolism kinetics, reversible inhibition kinetics, and inactivation kinetics. The chapter describes the advantages of using numerical methods when Michaelis–Menten assumptions do not hold.
Outspoken
发表于 2025-3-27 20:53:52
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Pillory
发表于 2025-3-28 01:49:51
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新陈代谢
发表于 2025-3-28 04:11:14
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caldron
发表于 2025-3-28 09:54:05
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令人苦恼
发表于 2025-3-28 11:17:49
Numerical Methods for Modeling Enzyme Kineticsed to solve differential equations. This chapter describes the use of numerical methods in solving differential equations and its applications in characterizing the complexities observed in enzyme kinetics. A discussion is included on the use of numerical methods to overcome limitations of explicit