miserly
发表于 2025-3-21 18:11:41
书目名称DNA-Encoded Chemical Libraries影响因子(影响力)<br> http://figure.impactfactor.cn/if/?ISSN=BK0260222<br><br> <br><br>书目名称DNA-Encoded Chemical Libraries影响因子(影响力)学科排名<br> http://figure.impactfactor.cn/ifr/?ISSN=BK0260222<br><br> <br><br>书目名称DNA-Encoded Chemical Libraries网络公开度<br> http://figure.impactfactor.cn/at/?ISSN=BK0260222<br><br> <br><br>书目名称DNA-Encoded Chemical Libraries网络公开度学科排名<br> http://figure.impactfactor.cn/atr/?ISSN=BK0260222<br><br> <br><br>书目名称DNA-Encoded Chemical Libraries被引频次<br> http://figure.impactfactor.cn/tc/?ISSN=BK0260222<br><br> <br><br>书目名称DNA-Encoded Chemical Libraries被引频次学科排名<br> http://figure.impactfactor.cn/tcr/?ISSN=BK0260222<br><br> <br><br>书目名称DNA-Encoded Chemical Libraries年度引用<br> http://figure.impactfactor.cn/ii/?ISSN=BK0260222<br><br> <br><br>书目名称DNA-Encoded Chemical Libraries年度引用学科排名<br> http://figure.impactfactor.cn/iir/?ISSN=BK0260222<br><br> <br><br>书目名称DNA-Encoded Chemical Libraries读者反馈<br> http://figure.impactfactor.cn/5y/?ISSN=BK0260222<br><br> <br><br>书目名称DNA-Encoded Chemical Libraries读者反馈学科排名<br> http://figure.impactfactor.cn/5yr/?ISSN=BK0260222<br><br> <br><br>
潜伏期
发表于 2025-3-21 20:54:02
Library Synthesis: Building Block Validation,nsuring the quality of a library. Here we describe the validation method used to assess the reactivity of potential building blocks to be included in a DNA-encoded library, with HATU acylation of carboxylic acid building blocks with an on-DNA amine substrate as an example.
Congestion
发表于 2025-3-22 03:11:38
Library Synthesis and Analytics,to billions of compounds can be prepared by a combination of chemical and enzymatic synthesis. Here we describe the analytics methods used in the library synthesis with one cycle of synthesis as an example.
我说不重要
发表于 2025-3-22 05:49:49
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fixed-joint
发表于 2025-3-22 11:29:13
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cultivated
发表于 2025-3-22 13:34:23
DNA-Compatible Nitro Reduction and Synthesis of Benzimidazoles,rary structure diversity is often limited to DNA-compatible chemical reactions in aqueous media. Herein, we describe a facile process for reducing aryl nitro groups to aryl amines by using sodium dithionite (Na.S.O.). The new protocol offers simple operation and circumvents the pyrophoric potential
cultivated
发表于 2025-3-22 17:07:42
DNA Encoding of Natural Products,mbinatorial synthesis. Natural products (NPs) are evolutionary optimized compounds that have played a key role in the history of human drug discovery. Herein, we describe a method for functionality-independent annotation of complex natural products with amplifiable DNA barcodes to generate a DNA-enc
违反
发表于 2025-3-23 00:32:07
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Isthmus
发表于 2025-3-23 01:26:28
One Bead-One Compound (OBOC) Peptidomimetic-Encoded Library Synthesis via Split-and-Pool Methods, of therapeutically important compounds with higher affinity and improved pharmacological properties against different protein targets..Here we describe a simple and general method for the submonomer solid phase synthesis of large one bead-one compound (OBOC) peptidomimetic libraries of structurally
网络添麻烦
发表于 2025-3-23 09:07:09
DNA Conjugates as Tool Compounds for DEL Selections,e ligand that binds to the target protein can be conjugated to DNA to mimic compounds contained in DEL libraries. The conjugate can be used as a ligand in preselection binding assays to validate a target protein and optimize selection methods and serve as a positive control in selection experiments.