DENT 发表于 2025-3-30 09:33:28
http://reply.papertrans.cn/25/2420/241990/241990_51.pngconsolidate 发表于 2025-3-30 14:17:03
http://reply.papertrans.cn/25/2420/241990/241990_52.png磨碎 发表于 2025-3-30 17:09:35
http://reply.papertrans.cn/25/2420/241990/241990_53.png被诅咒的人 发表于 2025-3-30 23:06:42
Click Chemistry for Cyclic Peptide Drug Design,cyclic peptidomimetic compounds. The usage of “click chemistry” reactions includes various topics: (a) mimicking peptide bonds; (b) synthesis of ordered structures; (c) ligation of peptidomimetic scaffolds; and most importantly in this chapter (d) cyclization of peptidomimetic scaffolds using the triazole ring as constraint of conformation.展览 发表于 2025-3-31 03:15:03
http://reply.papertrans.cn/25/2420/241990/241990_55.pngArresting 发表于 2025-3-31 06:14:41
Jinghang Lu,Baoze Wei,Xiaochao Hou,Yao Sunon and macrocyclization in order to limit a peptide’s conformational possibilities, to increase its chemical and enzymatic stability, to prolong the time of action, and to increase activity and selectivity toward the receptor.