DENT 发表于 2025-3-30 09:33:28

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consolidate 发表于 2025-3-30 14:17:03

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磨碎 发表于 2025-3-30 17:09:35

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被诅咒的人 发表于 2025-3-30 23:06:42

Click Chemistry for Cyclic Peptide Drug Design,cyclic peptidomimetic compounds. The usage of “click chemistry” reactions includes various topics: (a) mimicking peptide bonds; (b) synthesis of ordered structures; (c) ligation of peptidomimetic scaffolds; and most importantly in this chapter (d) cyclization of peptidomimetic scaffolds using the triazole ring as constraint of conformation.

展览 发表于 2025-3-31 03:15:03

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Arresting 发表于 2025-3-31 06:14:41

Jinghang Lu,Baoze Wei,Xiaochao Hou,Yao Sunon and macrocyclization in order to limit a peptide’s conformational possibilities, to increase its chemical and enzymatic stability, to prolong the time of action, and to increase activity and selectivity toward the receptor.
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查看完整版本: Titlebook: Cyclic Peptide Design; Gilles Goetz Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 Drug design.Small molecul