Folklore
发表于 2025-3-28 17:39:19
Design and Synthetic Strategies for Helical Peptides,” for traditional small molecules. Peptides, emerging as a new therapeutic modality, can efficiently mimic PPIs with their large scaffolds. Natural peptides are flexible and usually have poor serum stability and cell permeability, features that limit their further biological applications. To satisfy
小虫
发表于 2025-3-28 22:09:49
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GRIPE
发表于 2025-3-29 00:54:24
Frontier Between Cyclic Peptides and Macrocycles,tructural features that potentially modulate cellular permeability. Examples range from exclusively peptidic structures like cyclosporin A or phepropeptins to compounds with mostly non-peptidic character, such as telomestatin or largazole. Furthermore, semisynthetic approaches and synthesis platform
Promotion
发表于 2025-3-29 03:49:51
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Ablation
发表于 2025-3-29 09:33:27
Design of Oxytocin Analogs,y seven decades. Despite having rather poor drug-like properties, OT is used as a treatment for labor induction, postpartum hemorrhage, and lactation support. The potential use of OT in the treatment of central nervous system (CNS)-related diseases has recently renewed interest in the pharmacology o
cogitate
发表于 2025-3-29 13:25:22
DNA-Encoded Macrocyclic Peptide Library,a macrocyclic DNA-encoded library; how to perform selection, sequencing, and data analysis to identify potential active peptides; and how to synthesize off-DNA peptides to confirm activity. This approach provides an effective tool for pharmaceutical research based on peptides.
Indurate
发表于 2025-3-29 16:43:29
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价值在贬值
发表于 2025-3-29 22:03:37
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痛得哭了
发表于 2025-3-30 00:27:11
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手工艺品
发表于 2025-3-30 04:25:58
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