书目名称 | The UNC-53-mediated Interactome |
副标题 | Analysis of its Role |
编辑 | Amita Pandey,Girdhar K. Pandey |
视频video | http://file.papertrans.cn/922/921576/921576.mp4 |
概述 | The book presents C. elegans as model organism for the development of the nervous system translation.Discusses various disorders that are associated with improper wiring of the nervous system.Gives an |
丛书名称 | SpringerBriefs in Neuroscience |
图书封面 |  |
描述 | .This book gives an overview of various interactomes involved in dorsal ventral (DV) and anterior posterior (AP) guidance, their mechanisms of action, subcellular localizations, and functional roles. It will provide readers a better understanding of the development of the nervous system, which in turn will help to find cures to various neural and other disorders..In nematodes there are two types of guidance systems, including DV and AP guidance. The signaling process that guides the growth cones along the DV axis has remained intact in both vertebrates and invertebrates. The adaptor protein UNC-53 appears to play a part in migration along the AP axis in both worms and their human homologs. “Neuron Navigators” (NAV) are also involved in nervous system development . |
出版日期 | Book 2014 |
关键词 | C; elegans interactome; axon and cell migragion; connectome; develoment of the nervous system; downstrea |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-07827-4 |
isbn_softcover | 978-3-319-07826-7 |
isbn_ebook | 978-3-319-07827-4Series ISSN 2191-558X Series E-ISSN 2191-5598 |
issn_series | 2191-558X |
copyright | The Author(s) 2014 |