| 书目名称 | The Secret Lives of Transcription Factors |
| 副标题 | In Heterochromatin R |
| 编辑 | Willis X. Li,Louise Silver-Morse |
| 视频video | |
| 概述 | Presents a niche topic usually given a chapter in larger books.Broad reach across the sciences because transcription is a fundamental cellular and genetic process.Provides a cohesive, authoritative pr |
| 丛书名称 | SpringerBriefs in Biochemistry and Molecular Biology |
| 图书封面 |  |
| 描述 | This SpringerBrief explores unconventional functions of eight different transcription factors and concludes with a discussion of their biological significance and impact, including effects on processes within the cell nucleaus during development and in adult organisms. Chapter One details unconventional functions of the transcription factors GAGA, HP1, Rb, STAT, ATF-2 and NF-kB. Surprisingly, all of these transcription factors can be found in association with heterochromatin as well as euchromatin, and in some cases unconventional functions have been demonstrated for these heterochromatin-associated factors. Chapter Two focuses on the unconventional functions of STAT and HP1 and discusses their roles in the promotion of longevity, and in protection from cancer and DNA damage. Chapter Three explores the biological significance of the findings presented in the first two chapters and considers how global changes in the epigenome brought about by factors such as STAT and HP1 might affect processes within the cell nucleus during development and in adult organisms. This succinct yet thorough SpringerBrief is essential for researchers studying epigenetics, and to instructors of the sub |
| 出版日期 | Book 2023 |
| 关键词 | HP1; cell processes; epigenetics; gene transcription; Transcription Factors |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-031-29029-9 |
| isbn_softcover | 978-3-031-29027-5 |
| isbn_ebook | 978-3-031-29029-9Series ISSN 2211-9353 Series E-ISSN 2211-9361 |
| issn_series | 2211-9353 |
| copyright | Springer Nature Switzerland AG 2023 |
发表于 2025-3-21 16:23:02
