书目名称 | The Renin Angiotensin System in Cardiovascular Disease |
编辑 | Naranjan S. Dhalla,Sukhwinder K. Bhullar,Anureet K |
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概述 | Includes state-of-the-art research on the role of renin-angiotensin system.Discusses the interaction between different receptors and signaling pathways for the Renin-angiotensin system.Showcases diffe |
丛书名称 | Advances in Biochemistry in Health and Disease |
图书封面 |  |
描述 | This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number onecause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that th |
出版日期 | Book 2023 |
关键词 | cardiovascular physiology; Hypertension; vascular remodeling; atherosclerosis; arrhythmia; heart failure |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-031-14952-8 |
isbn_softcover | 978-3-031-14954-2 |
isbn_ebook | 978-3-031-14952-8Series ISSN 2512-2142 Series E-ISSN 2512-2150 |
issn_series | 2512-2142 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |