书目名称 | The Minimal Cell | 副标题 | The Biophysics of Ce | 编辑 | Pier Luigi Luisi,Pasquale Stano | 视频video | | 概述 | It gives an up-to-date view of experimental research on the construction of advanced cell models based on liposomes.Biophysical, biochemical, genetic and computational approaches are presented.One of | 图书封面 |  | 描述 | In the last ten years there has been a considerable increase of interest on the notion of the minimal cell. With this term we usually mean a cell-like structure containing the minimal and sufficient number of components to be defined as alive, or at least capable of displaying some of the fundamental functions of a living cell. In fact, when we look at extant living cells we realize that thousands of molecules are organized spatially and functionally in order to realize what we call cellular life. This fact elicits the question whether such huge complexity is a necessary condition for life, or a simpler molecular system can also be defined as alive. Obviously, the concept of minimal cell encompasses entire families of cells, from totally synthetic cells, to semi-synthetic ones, to primitive cell models, to simple biomimetic cellular systems. Typically, in the experimental approach to the construction of minimal the main ingredient is the compartment. Lipid vesicles (liposomes) are used to host simple and complex molecular transformations, from single or multiple enzymic reactions, to polymerase chain reactions, to gene expression. Today this research is seen as part of the broader | 出版日期 | Book 2011 | 关键词 | liposeomes (lipid vesicles); micro-compartmentation; origing of life; self-organization; synthetic biolo | 版次 | 1 | doi | https://doi.org/10.1007/978-90-481-9944-0 | isbn_softcover | 978-94-017-8158-9 | isbn_ebook | 978-90-481-9944-0 | copyright | Springer Science+Business Media B.V. 2011 |
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