书目名称 | The Adrenergic Receptors | 副标题 | In the 21st Century | 编辑 | Dianne M. Perez | 视频video | | 概述 | Includes supplementary material: | 丛书名称 | The Receptors | 图书封面 |  | 描述 | An authoritative review of the current state-of-the-art understanding of the structure and function ofthe adrenergic receptor subtypes, as well as of the role played by these receptors in physiological and pathophysiological settings. Topics range from structure-function studies and the imaging of adrenergic receptors to the use of genetically altered mouse models and pharmacogenomics. Highlights include a survey of the knockout and overexpressed mouse models, a review of the new ways that adrenergic receptors can signal, and the effects of polymorphisms on clinical outcomes and on potential gene therapy applications. The side-by-side comparison of all the adrenergic receptors (a1, a2, and b) provides the reader with an excellent survey of the field, including the rationale for designing better drugs to control blood pressure and heart function. | 出版日期 | Book 2006 | 关键词 | blood; blood pressure; gene; gene therapy; genomics; imaging; medicine; microarray; mouse; outcome; receptor s | 版次 | 1 | doi | https://doi.org/10.1385/1592599311 | isbn_softcover | 978-1-61737-559-0 | isbn_ebook | 978-1-59259-931-8Series ISSN 1048-6909 Series E-ISSN 2524-6488 | issn_series | 1048-6909 | copyright | Humana Press 2006 |
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