书目名称 | Telomeres and Telomerase in Cancer | 编辑 | Keiko Hiyama | 视频video | | 概述 | This book will focus on telomere and telomerase in human cancers and may provide medical doctors, pathologists, and translational cancer researchers with a deep understanding of these unique and fasci | 丛书名称 | Cancer Drug Discovery and Development | 图书封面 |  | 描述 | .Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.. | 出版日期 | Book 2009 | 关键词 | DNA; DNA Damage; Hematopoietic Malignancies; Lengthening of Telomeres; Telomerase Inhibitors; biology; can | 版次 | 1 | doi | https://doi.org/10.1007/978-1-60327-879-9 | isbn_softcover | 978-1-61737-888-1 | isbn_ebook | 978-1-60327-879-9Series ISSN 2196-9906 Series E-ISSN 2196-9914 | issn_series | 2196-9906 | copyright | Humana Press 2009 |
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