Titlebook: Systems Biology for Signaling Networks; Sangdun Choi Book 2010 Springer Science+Business Media, LLC 2010 Endoplasmatisches Reticulum.Micro

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Assembly of Logic-Based Diagrams of Biological Pathwaysems, even on a relatively small scale, are far too complicated to understand intuitively. Furthermore, enormous amounts of systems-level data pertaining to the nature of genes and proteins, and their potential cellular interactions, have now been generated, but we struggle to interpret these data. T

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Automating Mathematical Modeling of Biochemical Reaction Networksscuss how to automate each individual step and how to put these steps together. First, we create a topology of interconversion processes and mutual influences between reactive species. The Systems Biology Markup Language (SBML) encodes the model in a computer-readable form and allows us to add seman

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Strategies to Investigate Signal Transduction Pathways with Mathematical Modellinglling, simulation and theory. Systems biology is particularly suitable for the study of cell signalling systems because of the inherent complexity of the signalling networks, the amount and variety of the quantitative data combined for their analysis and some special features of cell signalling syst

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Inferring Transcriptional Regulatory Networkogical functions in living cells. In this chapter, we describe a series of new methodologies for identifying transcriptional modules and regulatory networks and examining their evolutionarily conserved and divergent patterns from gene expression and transcription factor data. The methods are based o

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