Titlebook: Systems Biology and Biotechnology of Escherichia coli; Sang Yup Lee Book 2009 Springer Science+Business Media B.V. 2009 Expression.Glucose

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Organisation of Complex , Promoters,n this regulation and the different mechanisms by which they control transcription initiation at simple and complex promoters are outlined. At some promoters, the actions of transcription factors are modulated by nucleoid associated proteins. Two examples where this occurs, the regulatory regions of the . and . genes, are described in detail.

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Genome-Scale Reconstruction, Modeling, and Simulation of , Metabolic Network,h key exemplary case studies of uses of the . metabolic reconstruction, and insights into the future of the field. As such, this chapter should serve as a guide to those interested in either expanding the application of the . reconstruction or adapting established applications to other organisms.

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Engineering , Central Metabolism for Enhanced Primary Metabolite Production, of such altered strains for metabolic engineering purposes for the improved production of specific reduced molecules for biofuels, chiral pharmaceutical intermediates, unconjugated colored compounds, and other valuable chemicals is presented.

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Ekaterina A. Mogilevskaya,Kirill V. Peskov,Eugeniy A. Metelkin,Galina V. Lebedeva,Tatiana Y. Plyusni

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Timo Hardiman,Karin Lemuth,Martin Siemann-Herzberg,Matthias Reuss