Titlebook: Systems Biology; Definitions and Pers Lila Alberghina,H.V. Westerhoff Book 2005 Springer-Verlag Berlin Heidelberg 2005 In silico.Modelling.

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Kinetic modelling of the , metabolism,predict how cell genome modifications can meet specific biotechnological and biomedical criteria. We have successfully applied the strategy for the development and applications of detailed kinetic models of catabolic and anabolic pathways of

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好色

No music without melody: How to understand biochemical systems by understanding their dynamics,s of concentration changes. Due to this development, it is now apparent that dynamics, e.g. nonlinear dynamics like oscillations carry important functionality and should not be neglected in the search for a full understanding of cellular processes. Examples are discussed in this contribution.

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Integration of metabolic and signaling networks,ir characteristic properties. The second part focuses on the development of integrated models of metabolism and signal transduction. The case of yeast cyclic AMP (cAMP) signaling and its interaction with energy metabolism and elements of the cell cycle machinery is used to exemplify this approach.

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Systems Biology: necessary developments and trends,n this context, we indicate what aspects of Systems Biology need to be stimulated most. We also touch on its effects on competitiveness of high-sophistication industries. Finally, we suggest special requirements that Systems Biology imposes on the organization and funding of Life Sciences research in the 21st century.

强有力

Book 2005 living cell, in silico); and new concepts and principles concerning interactions. This book defines the new field of systems biology and discusses the most efficient experimental and computational strategies. The benefits for industry, such as the new network-based drug-target design validation, and testing, are also presented..

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