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Titlebook: Systematic Exploration of Indolizine-Based Small Fluorescent Molecules; Synthesis, Analysis Youngjun Lee Book 2018 Springer Nature Singapo

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书目名称Systematic Exploration of Indolizine-Based Small Fluorescent Molecules
副标题Synthesis, Analysis
编辑Youngjun Lee
视频videohttp://file.papertrans.cn/885/884601/884601.mp4
概述Recognized as an outstanding Thesis by the Department of Chemistry, Seoul National University.A concise introduction to widely used fluorophores.Offers an interdisciplinary approach to unravel the det
丛书名称Springer Theses
图书封面Titlebook: Systematic Exploration of Indolizine-Based Small Fluorescent Molecules; Synthesis, Analysis  Youngjun Lee Book 2018 Springer Nature Singapo
描述This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter..Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working underlive cell conditions..Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the im
出版日期Book 2018
关键词Molecular Fluorescence; Organic Fluorophores; Photophysical Parameters; Indolizine-Based Seoul-Fluor Sy
版次1
doihttps://doi.org/10.1007/978-981-13-1645-6
isbn_softcover978-981-13-4660-6
isbn_ebook978-981-13-1645-6Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer Nature Singapore Pte Ltd. 2018
The information of publication is updating

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Youngjun Leee the source code. On top of these tools, a software tool, Diagnoser, is offered to facilitate experimenting with and developing new fault localization algorithms. Diagnoser takes a source code and its test suite as input and reports the coverage provided by the test cases and the suspiciousness sco
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theuse of automated tools, the tips are not specific to any one vendor solution. The tips cover general issues that are faced no matter the specific tool, and are broadly applicable, often even to manual testi978-1-4842-3161-6978-1-4842-3162-3
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2190-5053 e cell conditions..Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the im978-981-13-4660-6978-981-13-1645-6Series ISSN 2190-5053 Series E-ISSN 2190-5061
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Systematic Exploration of Indolizine-Based Small Fluorescent MoleculesSynthesis, Analysis
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Introduction,rational level of S. state. Finally, the fate of an excited molecule at the lowest lying first excited state results in radiative energy loss (fluorescence, 10. ~ 10. s), or nonradiative energy loss (quenching). For some molecules, especially with heavy atoms such as iodine, or bromine, intersystem
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Tetrazine-Containing Colorful Bioorthogonal Probes Based on the Indolizine Core Skeleton,ins in a nonspecific manner [.]. Moreover, extensive washing is required to remove an excess amount of fluorescent conjugates to get a higher signal-to-noise ratio. By taking advantage of bioorthogonal chemistry (highly specific and working in aqueous conditions), [.] researchers now can develop exq
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