Titlebook: Survivors of Childhood and Adolescent Cancer; A Multidisciplinary Cindy L. Schwartz,Wendy L. Hobbie,Kathleen S. Rucc Book 2015Latest editi

MIME

路标

The Ovary,l females possess their lifetime supply of oocytes with no new oogonia formed after birth. Active mitosis of oogonia occurs during fetal life, reaching a peak of six to seven million by 20 weeks of gestation and then rapidly declining to one to two million at birth. At the onset of puberty, only 300

sleep-spindles

引起

Genitourinary,ureters, bladder, urethra, prostate, vagina, and uterus. The effects on ovaries and testes are reviewed in Chaps. . and .. The most common pediatric cancers that occur in the GU tract include Wilms’ tumor, neuroblastoma, and rhabdomyosarcoma. The median age of children affected with these tumors ran

爱好

Musculoskeletal, Integument,are well known, it is important to realize that surgery and sometimes chemotherapy also affect the developing musculoskeletal system. In general, the treatment of sarcomas leads to the most severe late effects because the underlying malignancy originates in a muscle or bone and often an extremity. D

丰富

Breast Chapter,childhood cancer. Normal breast development can be impaired by exposure to radiation, prior surgery, and by decreased estrogen exposure associated with therapy-induced ovarian or hypothalamic disruption. Normal function of the breast as the lactation organ has not been well studied in survivors. Mos

ACTIN

Hematopoietic Stem Cell Transplantation,ssible by several factors, including expansion of the unrelated donor pool, advances in mobilization and collection of autologous cells, and reduced intensity conditioning regimens. Although transplant-related mortality and relapse remain obstacles, an increasing number of children are surviving fol

间接

Second Malignancies Following Treatment for Childhood Cancer,re one of the most devastating consequences of cancer therapy in children with cancer. Studies following large cohorts of childhood cancer survivors have reported a three- to sixfold increased risk of SMNs compared with the background incidence of cancer in the general population; this risk continue

露天历史剧

Endocrine Complications of Cancer Therapy,ate effects after localized or large volume irradiation, the differential sensitivity of functional subunits of the hypothalamus and other critical endocrine organs to radiation dose, the low-dose radiation effects in normal tissues, and the benefit of newer radiation methods and modalities.

惹人反感

Cardiovascular Effects of Cancer Therapy,y of potential late effects of cancer therapy to light. The developing cardiovascular system is particularly vulnerable to cardiotoxic cancer therapies such as anthracyclines and radiation. These treatment modalities have been found to result in chronic, progressive cardiac dysfunction occurring months to decades after treatment.