Titlebook: Surfactant Replacement Therapy; in Neonatal and Adul Burkhard Lachmann Conference proceedings 1988 Springer-Verlag Berlin Heidelberg 1988 A

胶水

Pulmonary Surfactant: Evolution of Functional Conceptsurface tension of water, 72 mN/m, ought to give an enormously high pressure in the tiny bubble, so that the gas inside the bubble should have been absorbed quickly by the surrounding saline solution. When this did not happen, but the bubble persisted, Pattle concluded that there must be a lining lay

闯入

Some Remarks on the Use of Physico-Chemical Methods in Lung Surfactant Research concerned the existence of a continuous liquid lining layer, the geometry of the alveoli and the relevance of surface tension [9, 10]. In the mid-sixties the oscillating bubble method (OBM) was introduced [11]. This method has certain advantages over the LWM: its small dimensions allow for a better

包裹

Diagnosis of Surfactant Defects in Newborn, Children and Adults in the Era of Surfactant Therapylavage, may not be representative of alveolar fluid. Secondly, there may be no reliable methods to quantify the surfactant pool. In this report it is proposed that surfactant diagnostics are of value when surfactant therapy is contemplated.

相符

Conference proceedings 1988dwide with tracheal instillation of surfactant, with most promising results. The type of surfactant used varies from pure natural extracts from bovine or pig lungs, to surfactant extracted from human amniotic fluid, to pure phospholipids. To date, however, there is still no surfactant commercially a

MOTIF

胆汁

Factors Affecting the Response to a Postnatal Single Dose of a Reconstituted Bovine Surfactant (Surfowever, the beneficial results have not been consistent [10]. In addition, the reasons for the variation in response and the identity of the non-responsive nature in some infants have not been clarified.

出汗

The European Multicenter Trial of Surfactant Replacement in Neonatal Respiratory Distress Syndromeced porcine lungs by a combination of washing, chloroform-methanol extraction, and liquid-gel chromatography. It contains 99% polar lipids, mainly phospholipids, and 1% hydrophobic, low molecular weight (< 15 kDa) proteins [1].

Kinetic

Commission

978-3-642-73307-9Springer-Verlag Berlin Heidelberg 1988

允许

Evaluation of Pulmonary SurfactantIt is established that pulmonary surfactant lining the lungs has several essential properties (Table 1), and any preparation to be used as a replacement must have those properties and, furthermore, should probably simulate those of the natural product as far as possible.