| 书目名称 | Structural and Functional Characterization of the Immunoproteasome |
| 编辑 | Eva Maria Huber |
| 视频video | |
| 概述 | Nominated as an outstanding Ph.D. thesis by the Technische Universität München, Germany.Detailed analysis of the X-ray structures of the murine immune- and constitutive proteasome.Yeast mutagenesis st |
| 丛书名称 | Springer Theses |
| 图书封面 |  |
| 描述 | In this acclaimed thesis, Eva Maria Huber reveals ground-breaking results by elucidating the crystal structure of the murine immunoproteasome in complex with a selective inhibitor. Huber does this by performing multidisciplinary methodologies including X-ray crystallography, fluorescence spectroscopy and mutagenesis experiments. Her exceptional results explore the immunoproteasome complex structures and are of outstanding importance for future scientific research especially in the pharmaceutical industry. These results will enable the functional analysis of individual proteasome subunits and support the development of novel drugs for autoimmune diseases such as multiple sclerosis or rheumatoid arthritis. |
| 出版日期 | Book 2013 |
| 关键词 | Antigen Generation; Drugs for Cancers and Autoimmune Diseases; Immunoproteasome X-ray Structure; Protea |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-01556-9 |
| isbn_softcover | 978-3-319-37810-7 |
| isbn_ebook | 978-3-319-01556-9Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
| issn_series | 2190-5053 |
| copyright | Springer International Publishing Switzerland 2013 |
发表于 2025-3-21 17:42:58
