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Titlebook: Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment; Mitchell S. Anscher,Kristoffer Valerie Book 2016 Springer

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The Role of Hypoxia in Radiation Response,croenvironment such as hypoxia, and also target pathways that may reduce radiation-induced normal tissue toxicity. With these concepts in mind, we review the biological consequences of tumor hypoxia and the effects of hypoxia/HIF on tumor radiation sensitivity as well as the effects of targeting the HIF/PHD axis for normal tissue radioprotection.
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The Role of MicroRNAs in Modulating Tissue Response to Radiation,pecific tumor initiation and progression. We further discuss clinical implications of using miRNA signatures as biomarkers for radiosensitivity and targeting specific miRNAs as therapeutic approaches.
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biology research, focusing on strategies designed to improve disease control and reduce the risk of long-term adverse effects on patients. As more and more patients are becoming long-term survivors, this strategy will become increasingly important--in radiation oncology and throughout the field of oncology.978-3-319-83326-2978-3-319-45594-5
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The Role of Cancer Stem Cells in Tumour Radioresponse, parameters such as the tumour volume for primary radio(chemo)therapy or the human papilloma virus infection status for head and neck squamous cell carcinoma, the utilization of putative CSC markers may help to predict radiotherapy outcome and allow for patient stratification for individualized treatment strategies.
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