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Titlebook: Stem Cells in the Lung; Development, Repair Ivan Bertoncello Book 2015 Springer International Publishing Switzerland 2015 bronchiolar airw

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楼主: 短暂
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Cellular Origins of Fibrotic Lung Diseasesational lung exposures. Fibrosis entails loss of somatic cell populations such as epithelial cells from their anatomic location along with proliferation, mobilization, infiltration, and differentiation of mesenchymal cells. In this chapter, I will review the present knowledge of the role of various
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Mesenchymal Stromal Cell-Based Therapies for Lung Diseaseunfortunately few treatments currently exist. Meeting this emerging clinical need will require a deeper understanding of how the human lung endures the innumerable relatively minor insults to which it is exposed each day; and how more extensive and elaborate repair occurs after severe injury. Failur
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Lung Vascular Regeneration and Repairent with that function, the lung vascular endothelial surface area exceeds that of any other vascular bed in the body. Lung vascular endothelial cells also provide direct growth promoting molecules and a platform for delivery of immunologic support to the alveolar epithelium. Given the critical impo
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Neural Regulation of Lung Developmentto the central nervous system. Here, we summarize what is known about the embryogenesis of intrinsic and extrinsic lung innervation and how it impacts on lung development. However, the precise ontogeny of the respiratory neuronal network and the signals by which it is regulated are, as yet, not fully elucidated.
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Regenerative Cells in the Ageing Lungm-progenitor cells in the PNX model are strikingly age dependent. This chapter focuses on important mechanisms of lung regeneration revealed by PNX that are thought to be vulnerable to healthy ageing and places those mechanisms in the context of chronic lung disease.
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Mesenchymal Stromal Cell-Based Therapies for Lung Diseasee of mesenchymal stromal cells in lung homeostasis and repair. Recent advances in our understanding of the pathogenesis of IPF will be highlighted as an example of how regenerative approaches could form the basis for the therapeutic advances required to meet the challenge of population ageing.
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Lung Vascular Regeneration and Repairnisms that involve both resident endothelial and circulating proangiogenic hematopoietic cells, before exploring lung endothelial regeneration and repair in compensatory lung growth and several well-established animal models of lung injury and highlight opportunities for cell therapy.
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2196-8985 from fetal development, postnatal growth and in adulthood.ScThis book presents a comprehensive overview of the current understanding of the organization of endogenous lung stem and progenitor cell compartments during fetal lung development, postnatal lung growth and in adulthood. Progressing stage b
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