Titlebook: Stem Cells; From Hydra to Man Thomas C. G. Bosch Book 2008 Springer Science+Business Media B.V. 2008 Hydra.Regeneration.Vertebrate.cell bio

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Melanocyte Stem Cells: As an Excellent Model to Study Stem Cell Biology,ch to study the molecular basis of stem cell regulation, because loss-of-function mutations in the genes responsible for MSC regulation are readily identifiable by a premature hair graying phenotype in mice. This implies the irresistible possibility that MSCs allows us to identify the genes involved

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Tumor Stem Cells: How to Define Them and How to Find Them?,athways are believed to be deregulated leading to uncontrolled self-renewal of cancer stem cells which generate tumors that are resistant to conventional therapies. Cancer stem cells as normal stem cells are likely to depend on a stem cell niche, a specialized microenvironment in which stem cells re

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Book 2008and the nature of questions, as well as a summary of the advances in our understanding of stem cells from a comparative point of view that has resulted from the development of new technology and the development of novel model organisms over the past few decades. As such this book is largely a horizo

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Book 2008ms such as the mouse and a few other vertebrate species has driven our understanding of basic biology of stem cells. The power and efficiency of studying model organisms, however, comes at a cost since a few species, obviously, do not reflect nature´s true diversity. Unfortunately, although all mult

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, Control of Organogenesis by ActivinA Treatment of Amphibian and Mouse Stem Cells,s from . undifferentiated ectodermal cells. These induction methods have been further extended to the differentiation of mouse embryonic stem cells .. These model systems for the development of various differentiated cell types, tissues, and even whole organs provide excellent tools for the study of developmental processes.

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, hESC Technology: State of the Art and Future Perspectives,t generating tissues suitable for the clinic. Discussed are laboratory techniques for controlling differentiation, for purifying homogenous populations, and for editing the genome of hESC. Also discussed are the strategies for ensuring the safety of hESC derived tissues for human patients, and an outlook on the future directions of hESC research.

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Stem Cell System of Sponge, cell system in metazoans, it is important to discover the molecular and cellular mechanisms of the stem cell system in sponges (Porifera), the evolutionarily oldest living multicellular organisms. The pluripotency of sponge cells called archeocytes is suggested by basic histological studies and it

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Stem Cells in Immortal ,,and endodermal epithelial stem cells, and interstitial stem cells. Over the last few years, stem cells in . became well-defined in cellular terms of their biology. More recently, efforts using the nearly unlimited potential for tissue manipulation combined with functional transgenesis have shed ligh

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Stem Cells in Planarian,ensively devoted themselves to studying mechanisms underlying regeneration, the planarian regeneration still remains mysterious phenomenon. Recently, modern approaches have been developed and incorporated in planarian research, and several mysterious points were clarified. Here, I focus on old probl