Titlebook: Stem Cell-Based Therapy for Lung Disease; Janette K. Burgess,Irene H. Heijink Book 2019 Springer Nature Switzerland AG 2019 regenerative m

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Paving the Road for Mesenchymal Stem Cell-Derived Exosome Therapy in Bronchopulmonary Dysplasia and ulmonary hypertension (PH), presents with elevated pulmonary vascular resistance associated with remodeling of the pulmonary arterioles. Despite notable advancements in neonatal medicine, there is a severe lack of curative treatments to help manage the progressive nature of these diseases. Numerous

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CRISPR/Cas9 Editing in Induced Pluripotent Stem Cells: A Way Forward for Treating Cystic Fibrosis? With the recent advances in state-of-the-art techniques such as induced pluripotent stem cells (iPSC), stem cell expansion, differentiation, and gene editing technologies, we now have the ability to expand patient-specific cells for therapeutic application. These autologous cells can be readily gen

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Preclinical Evidence for the Role of Stem/Stromal Cells in Targeting ARDSammatory response in the lung that can cause tissue remodeling, pulmonary dysfunction, and death [1]. ARDS is characterized by acute respiratory failure caused by an increase of fluids in the alveolar space. The breakdown of the immune response increases the permeability of the epithelial–endothelia

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The Safety and Efficiency of Addressing ARDS Using Stem Cell Therapies in Clinical Trialsdisease burden on patients. Incidence is rising, possibly due to greater awareness leading to more diagnoses rather than a change in the underlying rate. It arises from multiple etiologies, though pathogenic infection, termed pneumonia, is the most prevalent and widely studied. The distinct pathophy

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