Titlebook: Stem Cell-Based Therapy for Lung Disease; Janette K. Burgess,Irene H. Heijink Book 2019 Springer Nature Switzerland AG 2019 regenerative m

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Emanuele Rezoagli,Emma J. Murphy,John Laffey,Daniel O’Toole

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Preclinical Evidence for the Role of Stem/Stromal Cells in Targeting ARDSl barrier. This results in an increased filtration of protein-rich fluid from the vascular system into the alveolar spaces, with a subsequent lung edema and a decrease in the ability of gas exchange [2].

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The Safety and Efficiency of Addressing ARDS Using Stem Cell Therapies in Clinical Trialssiology and rapid evolution of ARDS makes it uniquely challenging with regard to therapeutics development and, to date, no medicines are licensed for specific therapy. Antibiotics, ventilation, and other organ support remain intervention standards.

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Chronic Lung Pathologies That Require Repair and Regeneration, increasing incidence with ageing, the full impact of these diseases is yet to be realised. For most chronic lung diseases there are limited treatments options, with the existing approaches mainly addressing symptom relief. Little progress has been made, in recent years, in the development of new th

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Stem/Progenitor Cell Populations Resident in the Lung and the Role of Stromal Support in Their Mainthly vascularized alveolar sacs, the alveoli, which are responsible for gas exchange. The gas exchange surface of the lungs makes up one of the largest surface areas of the human body. The alveoli receive air from the conducting airways, starting in the trachea, bifurcating into the bronchi and bronc

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