Titlebook: Stem Cell Research and Therapeutics; Yanhong Shi,Dennis O. Clegg Book 2008 Springer Science+Business Media B.V. 2008 RNA.biology.cell.cell

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Progressing Neural Stem Cell Lines to the Clinic,tegy. Initial clinical studies on cell implantation therapy in the brain used primary fetal tissue but progress has been made in developing expanded cell lines from somatic neural stem cells and embryonic stem cells. In addition, neural stem cell lines have been established by means of genetic modif

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The Analysis of MicroRNAs in Stem Cells,suring unique microRNAs are particularly useful in classifying stem cells or for studying mechanisms underlying their differentiation. Furthermore, straightforward bioinformatic and statistical methods are useful in investigating large sets of data to formulate hypotheses or identify microRNAs assoc

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Optimized Growth of Human Embryonic Stem Cells,e time for mouse ES cells. These original culture conditions were clearly not optimal, and since that time, several forces have driven improvements in human ES cell culture. These include the use of human and autologous feeder layers, the use of a serum replacement product, and the identification of

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Cell Transplantation Therapy for Myocardial Repair: Current Status and Future Challenges,r myocardial infarction. However, the mechanisms responsible for the observed therapeutic effects remain unknown. Different mechanisms have been proposed to explain the beneficial effects, including regeneration of contractile myocardial tissue, therapeutic neovascularization, prevention of left ven

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Use of Combinatorial Screening to Discover Protocols That Effectively Direct the Differentiation ofunity to perform developmental studies . and promising unlimited supplies of somatic cells for numerous biomedical applications including transplantation medicine. Reliably controlling the differentiation of ESCs . by conventional methods requires an understanding of complex developmental pathways,

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Adult Stem Cell Therapies for Tissue Regeneration: , Expansion in an Automated System,ssue types. Many questions exist in the field of cell therapy, from understanding the basic mechanisms of action, to the optimal methods for preparing and administering cells to the patient. Answers to these questions will help determine the best cell source, optimal protocols for . manipulation of