Titlebook: Stability and Characterization of Protein and Peptide Drugs; Case Histories Y. John Wang,Rodney Pearlman Book 1993 Springer Science+Busines

antidote

Stability of Adrenocorticotropic Hormone (ACTH) and Pathways of Deamidation of Asparaginyl Residue , corticosterone, aldosterone, and a number of weakly androgenic substances by activating adenyl cyclase in the cell membranes (Haynes and Larner, 1975). The activity of ACTH is destroyed by the proteolytic enzymes of the gastrointestinal tract; therefore, the hormone is ineffective when given orall

acrimony

Stability and Characterization of Human Interleukin-1,,and inflammatory responses. Many activities have been attributed to hIL-1, which include stimulation of murine thymocyte proliferation ., production of other cytokines (e.g., IL-2, IL-6, interferons, colony-stimulating factors), activation of lymphocytes, endogenous pyrogenicity, fibroblast prolifer

Vulnerable

Ige326

量被毁坏

TSH582

窃喜

Leuprolide and Other LH-RH Analogues,work that has been done to stabilize and to improve the activity of LH-RH analogues in order to make clinical application possible. Discussions of marketed and developmental drugs for diseases mediated by gonadotropins are included.

改良

Stability of Adrenocorticotropic Hormone (ACTH) and Pathways of Deamidation of Asparaginyl Residue s and Larner, 1975). ACTH rapidly disappears from the circulation following its intravenous administration in man; the plasma half-life is about 15 min. No significant biological activity is present in the urine (Haynes and Larner, 1975).

Brochure

Stability and Characterization of Human Growth Hormone,d to contain from 5 to 10 mg hGH (Daughaday, 1985). This chapter describes the history and clinical uses of the hormone, methods used for its characterization and analysis, and includes a discussion of hGH degradation reactions and its stability profile as well as a description of various hGH formulations.

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