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Titlebook: Spinal Opiate Analgesia; Experimental and Cli Tony L. Yaksh,Hermann Müller Book 1982 Springer-Verlag Berlin Heidelberg 1982 Analgesia.Anäst

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发表于 2025-3-21 19:10:02 | 显示全部楼层 |阅读模式
书目名称Spinal Opiate Analgesia
副标题Experimental and Cli
编辑Tony L. Yaksh,Hermann Müller
视频videohttp://file.papertrans.cn/875/874412/874412.mp4
丛书名称Anaesthesiologie und Intensivmedizin‘ Anaesthesiology and Intensive Care Medicine
图书封面Titlebook: Spinal Opiate Analgesia; Experimental and Cli Tony L. Yaksh,Hermann Müller Book 1982 Springer-Verlag Berlin Heidelberg 1982 Analgesia.Anäst
描述The recent development of the use of spinal opiates as a rational therapy for pain rests on clear and certain experimental data. We have long known the spinal cord to be a highly complex structure. Anatomical studies of the substantia gelatinosa have repeatedly demonstrated signs of massive synaptic interaction between primary afferents, descending pathways and intrinsic neurons. Yet, to date that knowledge, insofar as clinical therapy is concerned, has permitted us only to destroy certain connections within the spinal cord in the hopes that the substrate mediating pain could be anatomically differentiated from those which mediate other function. Though cordotomies are clearly effective under certain circumstances, they suffer from the fact the spinal cord is not organized in such an anatomically discrete fashion as is often times drawn in basic medical text. Rather, functions intertwine exquisitely and specific physical interventions are no more likely to produce a specific effect than smashing of the fmgertip with a hammer will produce just a loss of the fingernail. The development of specific therapies of the spinal cord has come about by our growing aware­ ness of the intricate
出版日期Book 1982
关键词Analgesia; Anästhesie; Opiat; Opiate; Spinalanästhesie; complications; pain; surgery
版次1
doihttps://doi.org/10.1007/978-3-642-68261-2
isbn_softcover978-3-540-11036-1
isbn_ebook978-3-642-68261-2Series ISSN 0171-1814
issn_series 0171-1814
copyrightSpringer-Verlag Berlin Heidelberg 1982
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发表于 2025-3-21 22:03:31 | 显示全部楼层
Epidural Low-Dose Morphine and Postoperative Pain: A Controlled Study,a mean total dose of 35 mg of morphine parenterally with a mean pain score of 3.1. In contrast, the study group received a mean dose of 6.7 mg epidurally with a mean pain score of 1.3. No side effects were observed.
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Book 1982e spinal cord to be a highly complex structure. Anatomical studies of the substantia gelatinosa have repeatedly demonstrated signs of massive synaptic interaction between primary afferents, descending pathways and intrinsic neurons. Yet, to date that knowledge, insofar as clinical therapy is concern
发表于 2025-3-22 08:57:10 | 显示全部楼层
Peridural Bupivacaine and Morphine for Residual Pain After Peripheral Vascular Surgery,n = 7), bradycardia (n = 3) and urinary retention (n = 4). . showed a poorer analgesic response and no significant effect on other measures. . patients showed an analgesia comparable to that of group 1, with no effect on cardiovascular measures, but produced urinary retention (n = 3).
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The Use of Epidural Buprenorphine for the Treatment of Postoperative Pain, 10% of the cases which received the lignocaine and buprenorphine combination treatment. Aside from vomiting in several patients, no other side effects, including urine retention, itching, headache or respiratory depression was observed.
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The Control of Postoperative Pain by Thoracic Fentanyl Epidural and its Effect Upon the Stress RespGroup 1 showed low pain and sedation scores though higher nausea scores than those observed in Group 2. Postoperative respiratory function was significantly better urine output and nasogastric output was significantly greatry depression were observed.
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Theoretical Aspects and Practical Considerations Concerning Selective Opiate-Analgesia, and the observation that locally applied opiates would inhibit the discharge of nociceptive neurons, represents the substrate whereby animal and subsequent human investigations observed a powerful antinociceptive effect of spinally administered opiates..The clinical use of spinal opiate action must
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